Last week, at the American Academy of Neurology annual meeting, Dr. Amit Bar-Or received the John Dystel Prize for Multiple Sclerosis Research for his multiple achievements that have advanced our knowledge of neuroimmunology, precision medicine, and biomarkers in MS. We talked with Dr. Bar-Or about how some of the latest discoveries in MS research would impact patient care.
Tolebrutinib, an investigational disease-modifying therapy, is currently making its way through the FDA's regulatory process. Last week, the results of the Phase 3 clinical trials for Tolebrutinib were published, and we're sharing the details.
We'll also tell you about MindGlide, an AI-powered tool for analyzing MRI scans that will significantly reduce MRI exam times.
We're talking about the results of the Phase 3 clinical trial for high-dose Ocrevus.
And we'll tell you about a cell therapy that doesn't use stem cells that successfully repaired myelin in the mouse model of MS — twice!
We have a lot to talk about! Are you ready for RealTalk MS??!
Congratulations to Dr. Stephen Hauser and Dr. Alberto Ascherio :22
This Week: The impact of breakthrough MS research on MS care 2:17
Results of the phase 3 clinical trials for Tolebrutinib have been published 3:07
An AI-powered tool for analyzing MRI scans will significantly reduce MRI exam times for patients 4:21
Results of the phase 3 clinical trial for high-dose Ocrevus 8:13
A cell therapy that doesn't use stem cells has successfully repaired myelin in the mouse model of MS — twice! 10:14
Dystel Prize winner Dr. Amit Bar-Or discusses how some of the latest discoveries in MS research will impact MS care 12:39
Share this episode 22:36
Have you downloaded the free RealTalk MS app? 22:56
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Become an MS Activist
Web: https://nationalmssociety.org/advocacy
Email: msactivist@nmss.org
RealTalk MS Episode 310: The Face Laughs While The Brain Cries: The Education of a Doctor with Dr. Stephen Hauser
https://realtalkms.com/310
RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh
https://realtalkms.com/ectrims244
VIDEO: RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh
https://youtu.be/zcBmAHRTotA
VIDEO: RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Nonrelapsing Secondary Progressive MS with Dr. Robert Fox
https://youtu.be/tJQ93qdlXrU
STUDY: Tolebrutinib Versus Teriflunomide in Relapsing Multiple Sclerosis
https://nejm.org/doi/full/10.1056/NEJMoa2415985
STUDY: Tolebrutinib in Nonrelapsing Secondary Progressive Multiple Sclerosis
https://nejm.org/doi/full/10.1056/NEJMoa2415988
Enabling New Insights from Old Scans By Repurposing Clinical MRI Archives for Multiple Sclerosis Research
https://www.nature.com/articles/s41467-025-58274-8
Fibroblast Technology
https://fibrobiologics.com/technology/#cnsms
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RealTalk MS Episode 398
Guests: Dr. Amit Bar-Or