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Episode 416: The Updated McDonald Diagnostic Criteria for MS with Dr. Andrew Solomon


Since 2001, clinicians have relied on the McDonald Diagnostic Criteria as the gold standard for diagnosing someone with multiple sclerosis. As science continues to add to our understanding of MS, the McDonald Criteria have been updated in 2005, 2010, 2017, and most recently in 2024.

This latest iteration of the McDonald criteria will be published in September, and today, Dr. Andrew Solomon is giving us a preview of what these changes are, what they mean, and how they're going to improve the process of diagnosing someone with MS.

We'll also share results of a study that show MS may actually start 15 years before someone experiences their first MS symptom.

We'll tell you about a study that shows a decline in the number of people with MS who are progressing to secondary progressive MS.

We'll give you all the details so you can participate in the Shaping Tomorrow Together initiative with the FDA.

And we'll remind you that Burgers to Beat MS Day is just two days away!

We have a lot to talk about! Are you ready for RealTalk MS??!


This Week: Updated criteria for diagnosing MS  :22

Study results show that MS actually starts many years before the first symptom  1:21

Study shows a decline in the number of people progressing to secondary progressive MS  7:40

A unique opportunity for you to impact future treatments and share your experience of living with MS with the FDA   9:51

We're just 2 days away from Burgers to Beat MS Day!  13:06

Dr. Andrew Solomon shares a preview of the updated McDonald Diagnostic Criteria for MS  14:40

Share this episode  26:20

Coming next week  26:41


SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/416

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!


LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

PARTICIPATE: Take the Shaping Tomorrow Together Survey
https://s.alchemer.com/s3/Perspectives-on-MS

REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA
https://nmss.quorum.us/event/25463

STUDY: Health Care Use Before Multiple Sclerosis Symptom Onset
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2837128

STUDY: Health Care Use Before Multiple Sclerosis Symptom Onset (PLAIN ENGLISH VERSION)
https://tremlettsmsresearchexplained.wordpress.com/2025/08/05/healthcare-use-before-multiple-sclerosis-symptom-onset-explained

STUDY: Multiple Sclerosis From Onset to Secondary Progression: A 30-Year Italian Register Study
https://researchgate.net/publication/392714813_Multiple_sclerosis_from_onset_to_secondary_progression_a_30-year_Italian_register_study

DONATE: Burgers To Beat MS
https://burgerstobeatms.ca

Join the RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

Download the RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

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Give RealTalk MS a rating and review
http://www.realtalkms.com/review


Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 416
Guest: Dr. Andrew Solomon

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