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Past Podcast Episodes

Episode 413: How AI Will Impact MS Patient Care with Dr. Brad Willingham


We're witnessing the early stages of a paradigm shift, as artificial intelligence is beginning to impact virtually every aspect of healthcare, from research to patient care. And there's much, much more to come.

Dr. Brad Willingham

This week, Dr. Brad Willingham, the Director of MS Research at Shepherd Center in Atlanta, joins me to discuss how AI will impact MS patient care.

We'll also share the encouraging results from a Phase 2 open-label extension study for Fenebrutinib, an investigational disease-modifying therapy.

We'll tell you about study results that show exercise interventions that follow physical activity guidelines for MS can have a significant impact on MS-related depression.

And we're sharing the results of a study that illustrate what can happen when you delay starting a disease-modifying therapy.

We have a lot to talk about! Are you ready for RealTalk MS??!


This Week: How AI will impact MS patient care  :22

Fenebrutinib shows positive results after one-year extension study  1:33

MS-related depression can be significantly eased through exercise intervention that follows physical activity guidelines for MS  3:36

What happens when you delay starting disease-modifying therapy?   8:46

Dr. Brad Willingham discusses how artificial intelligence is impacting all aspects of healthcare  14:29

Share this episode  33:18

Have you downloaded the free RealTalk MS app?  33:38


SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/413

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!


LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Become an MS Activist
https://nationalmssociety.org/advocacy

STUDY: Safety and Efficacy of Fenebrutinib in Relapsing Multiple Sclerosis (FENopta): A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase 2 Trial and Open-Label Extension
https://thelancet.com/journals/laneur/article/PIIS1474-4422(25)00174-7/abstract?rss=yes

STUDY: Effects of Meeting Exercise Guidelines on Depression and Anxiety in Multiple Sclerosis: A Systematic Review and Meta-Analysis
https://tandfonline.com/doi/full/10.1080/09593985.2025.2518261

Exercise and Physical Activity Recommendations for ALL People with MS
https://nationalmssociety.org/news-and-magazine/news/exercise-and-physical-activity-recommend

STUDY: Delayed Access and Adherence are Real-World Challenges That Compromise Effectiveness of Natalizumab in Multiple Sclerosis
https://sciencedirect.com/science/article/abs/pii/S2211034825003694

Join the RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

Download the RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

Download the RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

Give RealTalk MS a rating and review
http://www.realtalkms.com/review


Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 413
Guest: Dr. Brad Willingham

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Filed Under: Uncategorized

Episode 412: Understanding Late-Onset MS with Dr. Jacqueline Nicholas


More people over the age of 50 are being diagnosed with MS than ever before. When you consider the other health conditions that often develop as we age, and you add the fact that our immune system changes with age, there's a lot to think about when it comes to diagnosing and treating late-onset MS.

Dr. Jacqueline Nicholas

This week, Dr. Jacqueline Nicholas, the System Chief of Neuroimmunology and Multiple Sclerosis at the OhioHealth Multiple Sclerosis Center, joins me to help us better understand late-onset MS.

We'll also tell you about research results that could lead to a simple blood test that can predict MS years before someone experiences a single symptom.

You'll learn about an ultra-high resolution brain imaging tool that could open the door to precision neuroscience and revolutionize the treatment of neurological disorders

The FDA wants to talk with people about what living with MS is like, and what they're looking for in future treatments. We'll tell you how and where to register for an informational webinar that will give you all the details about the Shaping Tomorrow Together initiative.

And if you're in or around Northern California, we'll remind you that you can join us this Saturday in Napa Valley at Crush MS!

We have a lot to talk about! Are you ready for RealTalk MS??!


This Week: Understanding Late-Onset MS  :22

How a simple blood test may predict MS years before someone experiences any symptoms  1:34

How a new ultra-high resolution brain imaging tool may revolutionize the treatment of neurological disorders  6:40

Are you interested in telling the FDA what it's like living with MS, and what you want in future treatments?   8:53

Are you ready to support MS research while spending the afternoon in a Napa Valley vineyard? Get all the details to attend Crush MS  10:29

Dr. Jacqueline Nicholas discusses what's different and what's the same in treating late-onset MS  12:09

Share this episode  29:26

Have you downloaded the free RealTalk MS app?  29:46


SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/412

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!


LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Become an MS Activist
https://nationalmssociety.org/advocacy

STUDY: Early Identification of Individuals at Risk for Developing Multiple Sclerosis by Quantification of EBNA-1-381-452-Specific Antibody Titers
https://nature.com/articles/s41467-025-61751-9

REGISTER: Informational Webinar on the FDA “Shaping Tomorrow Together” Listening Session
https://nmss.zoom.us/webinar/register/WN_hHdHhEE3TBmPJ2glcgME0Q#/registration

EVENT: Crush MS
https://crushms.org

Join the RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

Download the RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

Download the RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

Give RealTalk MS a rating and review
http://www.realtalkms.com/review


Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 412
Guest: Dr. Jacqueline Nicholas

Privacy Policy

 

Filed Under: Uncategorized

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