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Past Podcast Episodes

Episode 425: The ECTRIMS 2025 Deep Dive with Dr. Bruce Bebo


Just about a month ago, 9,600 researchers, clinicians, and representatives from patient advocacy organizations gathered in Barcelona for the European Committee on Treatment and Research in MS annual scientific congress, better known as ECTRIMS, the largest MS research conference in the world.

Bruce Bebo

Now that he's had an opportunity to review his notes and digest all of the science presented at ECTRIMS 2025, Dr. Bruce Bebo, the National MS Society's Executive Vice-President of Research, returns to the podcast to take us on a deep dive covering some of the most important research presented this year.

We're also talking about next-generation CAR T-cell therapy for MS, and we'll explain why it's such exciting news.

We're sharing details about a DNA-based therapy for overactive bladder that just received fast-track status from the FDA.

We'll tell you about a new effort to develop a simple blood test that will detect MS progression.

We have some news to share about the RealTalk MS app. And we want to remind you to check out our ECTRIMS Extra Conversations video playlist on the RealTalk MS YouTube channel!

We have a lot to talk about! Are you ready for RealTalk MS??!


This Week: A deep dive into the research presented at ECTRIMS 2025  :22

Kernal Biologics received $48 million grant for the next-generation CAR T-Cell therapy  2:35

FDA grants fast track designation to DNA-based therapy to treat overactive bladder  6:02

Octave Bioscience receives grant to develop a blood test to detect MS progression  8:30

News about our app  9:42

Have you checked out our ECTRIMS Extra Conversations YouTube playlist?  10:30

Dr. Bruce Bebo discusses some of the most important research presented at ECTRIMS 2025  11:06

Share this episode  32:26

Next week's episode  32:47


SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/425

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!


LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

PARTICIPATE: Take the Shaping Tomorrow Together Survey
https://s.alchemer.com/s3/Perspectives-on-MS

REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA
https://nmss.quorum.us/event/25463

SIGN UP: Become an MS Activist
https://nationalmssociety.org/advocacy

LISTEN: RealTalk MS Ep 422: From ECTRIMS 2025 with Dr. Bruce Bebo and Kristine Werner Ozug
https://realtalkms.com/422

WATCH: The RealTalk MS ECTRIMS Extra Conversations video playlist on YouTube
https://realtalkms.com/ectrims2025

JOIN: The RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

DOWNLOAD: The RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

DOWNLOAD: The RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

REVIEW: Give RealTalk MS a rating and review
http://www.realtalkms.com/review


Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 425
Guests: Dr. Bruce Bebo

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Filed Under: Uncategorized

Episode 424: I’m a Participant in a Clinical Trial for CAR T-Cell Therapy and MS with Jan Janisch-Hanzlik


Jan Janisch-Hanzlik lives with MS and is a participant in one of the clinical trials evaluating the safety and efficacy of CAR-T cell therapy for MS. Jan is the first person in the world to receive this one-and-done treatment, and this week, she's joining me to share her experience participating in the clinical trial. But you'll be especially interested in hearing how CAR-T cell therapy has impacted Jan's MS.

Jan Janisch-Hanzlik

Open enrollment for people with Medicare and for those who get their health insurance through the ACA healthcare.gov Marketplace begins this week, and we're talking about some of the reasons you want to pay particular attention to your 2026 health insurance options.

As the U.S. federal government shutdown enters its third week, we're reviewing some of the ways that the shutdown may affect someone living with MS.

And we're giving you a reminder about how you can add your voice and share your story of living with MS with the FDA by participating in the Shaping Tomorrow Together initiative.

We have a lot to talk about! Are you ready for RealTalk MS??!


This Week: A first-hand account of an important clinical trial, open enrollment begins, and how the government shutdown may affect people with MS  :22

Open enrollment for Medicare and Marketplace enrolees begins  :22

How the federal government shutdown could affect people living with MS  4:29

Your opportunity to tell the FDA what it's like to live with MS  8:57

Jan Janisch-Hanzlik shares her experience participating in a CAR-T cell therapy clinical trial, and how the treatment has impacted her MS  11:28

Share this episode  31:38

Next week's episode  31:57


SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/424

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!


LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

PARTICIPATE: Take the Shaping Tomorrow Together Survey
https://s.alchemer.com/s3/Perspectives-on-MS

REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA
https://nmss.quorum.us/event/25463

SIGN UP: Become an MS Activist
https://nationalmssociety.org/advocacy

JOIN: The RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

DOWNLOAD: The RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

DOWNLOAD: The RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

REVIEW: Give RealTalk MS a rating and review
http://www.realtalkms.com/review


Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 424
Guest: Jan Janisch-Hanzlik

Privacy Policy

 

Filed Under: Uncategorized

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